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Injectable DNA-derived biostimulators that repair scalp tissue at a cellular level — creating a healthier environment for follicle function and supporting improved hair density.
Scalp polynucleotides apply the same regenerative science used for skin rejuvenation directly to the scalp — using DNA-derived biostimulators to repair scalp tissue, reduce inflammation and create a healthier environment for hair follicles.
PDRN molecules injected into the scalp stimulate fibroblasts and support angiogenesis (new blood vessel formation), improving the vascular supply to hair follicles and reducing the inflammatory processes that contribute to hair thinning. The result is a healthier scalp environment that supports better follicle function and improved hair quality.
At DermaMedica, scalp polynucleotides are most often used as part of a comprehensive hair restoration protocol — combined with PRP for growth factor stimulation and exosomes for cellular signalling.
The scalp is cleansed and topical anaesthetic applied. The treatment areas are mapped based on your pattern of thinning.
Polynucleotide solution is injected using fine needles across the scalp in the thinning areas — delivering biostimulators directly to the follicle level.
The PDRN binds to A2A receptors in scalp tissue, reducing inflammation, stimulating fibroblast activity and improving blood supply to follicles — creating conditions for healthier growth.
PRP delivers growth factors from your own blood to stimulate follicle activity. Polynucleotides repair scalp tissue at a cellular level and reduce inflammation. Both are effective individually — combined, they address different aspects of the hair loss process simultaneously for superior results.
Topical anaesthetic is applied before treatment. Most patients find it well-tolerated.
3–6 sessions for an initial course, spaced 3–4 weeks apart. Maintenance sessions every 6–12 months.
Yes — and this is our preferred approach for most patients seeking hair restoration. The combination addresses multiple mechanisms of hair loss simultaneously.
Medical note: All treatments at DermaMedica are administered by, or under the supervision of, GMC-registered doctors. A face-to-face medical consultation is required before treatment. Not suitable during pregnancy or breastfeeding. Full safety information is provided at consultation.
Every patient is different. If this treatment isn't the right fit, one of these alternatives may be exactly what you need.
Combine scalp polynucleotides with PRP hair restoration for a comprehensive multi-mechanism approach to hair density improvement.
Scalp exosome therapy complements polynucleotides by adding cellular signalling molecules alongside cellular repair.
Blood testing to identify nutritional deficiencies (ferritin, B12, vitamin D, thyroid) that may be contributing to hair loss.
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Every visit begins with a personalised consultation. Our team will guide you to the right treatment for your skin and goals.