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All the benefits of a high-intensity peel without the downtime or heavy shedding — this advanced formula brightens, firms and stimulates the deep dermis for visible, lasting results.
PRX-T33 is an advanced skin-perfecting treatment that provides the clinical benefits of a deep chemical peel without the traditional downtime, heavy shedding or weeks of recovery. It works by stimulating the deeper dermis through a unique formula combining high-concentration trichloroacetic acid (TCA) with hydrogen peroxide and kojic acid — but without causing surface peeling.
The result is a visibly brighter, firmer complexion with improved texture — accessible to patients who want genuine clinical results but cannot afford the social downtime of a conventional peel. There is no heavy flaking or raw skin; most patients return to normal activities and wear makeup within 24 hours.
At DermaMedica, PRX-T33 is often used as part of a broader skin quality protocol or before events where a visible improvement in skin quality is desired quickly.
The skin is cleansed and degreased. For optimal results, a course of preparatory skincare may be recommended in the weeks before treatment.
The PRX-T33 solution is applied and massaged into the skin in cycles. The formulation stimulates the deep dermis without causing surface disruption — so there is no traditional acid 'frosting' or peeling.
The treatment activates keratinocytes and fibroblasts in the deep dermis, stimulating collagen production and skin renewal. An immediate glow is visible from the first session.
The unique combination of TCA with hydrogen peroxide (H₂O₂) neutralises the surface action of the acid while still allowing the active ingredients to penetrate and stimulate the deeper dermis. This is what makes PRX-T33 unique — deep stimulation without surface disruption.
Most patients can. You will be red for 24–48 hours but there is no peeling or flaking. Many patients schedule PRX-T33 for a Thursday or Friday and are comfortable at work or socially by the weekend.
A course of 3–4 sessions spaced 2–3 weeks apart is recommended for optimal results. Maintenance sessions every 3–4 months help sustain the improvement.
Yes — PRX-T33 is suitable for all Fitzpatrick skin types, making it one of the most versatile brightening treatments available. It does not carry the risk of post-inflammatory hyperpigmentation that some other peels do.
A conventional chemical peel (such as TCA or phenol) causes significant surface disruption and visible peeling over 5–10 days. PRX-T33 achieves deep stimulation without surface disruption, making it a 'no downtime' alternative suitable for busy patients.
Yes — it combines well with microneedling (at a separate session), mesotherapy and home skincare. Your clinician will advise on the best protocol for your skin.
Medical note: All treatments at DermaMedica are administered by, or under the supervision of, GMC-registered doctors. A face-to-face medical consultation is required before treatment. Not suitable during pregnancy or breastfeeding. Full safety information is provided at consultation.
Every patient is different. If this treatment isn't the right fit, one of these alternatives may be exactly what you need.
Alternate microneedling and PRX-T33 in your treatment programme for comprehensive resurfacing, collagen stimulation and brightening.
A HydraFacial before or after a course of PRX-T33 keeps pores clear and skin optimally hydrated for enhanced results.
Profhilo maintains and enhances the skin quality improvements achieved by PRX-T33 with deep hydration and collagen stimulation.
Still unsure? Our consultation is always free and never high-pressure.
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Every visit begins with a personalised consultation. Our team will guide you to the right treatment for your skin and goals.