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The UK's most popular skin booster — ultra-pure, high-concentration hyaluronic acid that disperses beneath the skin to hydrate, firm and remodel from within.
Profhilo is unlike any other injectable skin treatment. Its ultra-high concentration of pure hyaluronic acid — the highest available in an injectable — is formulated to flow and disperse freely beneath the skin rather than staying in one place like a conventional filler.
This unique behaviour allows Profhilo to hydrate large areas of the face (and body) from within, whilst simultaneously stimulating four types of collagen and elastin. The result is skin that looks and feels genuinely healthier — plump, luminous, and more resilient — not simply fuller.
Profhilo is hailed as a revolution in skin bio-remodelling and is one of the most in-demand treatments at DermaMedica. It is ideal for patients experiencing early skin laxity, crepey texture, or a loss of skin quality and glow that cannot be addressed by topical skincare alone.
Profhilo is injected using the BAP (Bio Aesthetic Points) technique — five precise anatomical points on each side of the face that maximise natural diffusion of the product across the entire treatment area.
Within days of injection, the hyaluronic acid disperses freely through the tissue, attracting water and deeply hydrating the skin from within — creating the characteristic Profhilo glow.
Simultaneously, Profhilo stimulates four types of collagen and elastin, rebuilding the structural support network of the skin for lasting firmness and resilience beyond the treatment period.
While both use hyaluronic acid, Profhilo is formulated differently — it is a bio-remodeller, not just a hydrator. Its unique thermally bonded HA disperses freely rather than staying in a localised area, stimulating four types of collagen and elastin in the process.
A standard Profhilo treatment consists of two sessions, four weeks apart. This constitutes a full course. After this, maintenance sessions every 6 months help sustain and build on the results.
Yes — Profhilo can be used on the neck, décolletage, hands, inner arms and knees where crepey skin or laxity is a concern. Body treatments follow a different protocol to facial treatments.
Profhilo combines beautifully with almost any other treatment. It is commonly paired with anti-wrinkle injections, polynucleotides, microneedling, and dermal fillers — it improves overall skin quality, making other treatments look even better.
No — Profhilo does not add significant volume. It is a skin quality treatment, not a volumiser. If you are seeking volume, dermal fillers or Sculptra are more appropriate.
Many patients notice a glow and improvement in hydration within 1–2 weeks of the first session. Firming and structural improvements develop over 4–8 weeks as collagen stimulation occurs.
Virtually none. Small bumps at injection points can be visible for a few hours but typically resolve by the end of the day. Most patients return to normal activities immediately.
Medical note: All treatments at DermaMedica are administered by, or under the supervision of, GMC-registered doctors. A face-to-face medical consultation is required before treatment. Not suitable during pregnancy or breastfeeding. Full safety information is provided at consultation.
Every patient is different. If this treatment isn't the right fit, one of these alternatives may be exactly what you need.
Profhilo hydrates and stimulates collagen; polynucleotides repair at a cellular level. Together they deliver the most comprehensive skin quality improvement.
Combine Profhilo's skin quality improvement with anti-wrinkle injections for a complete facial refresh — addressing both skin health and muscle-related lines.
Microneedling creates micro-channels that dramatically enhance Profhilo absorption when used in sequence — a powerful combination protocol.
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Every visit begins with a personalised consultation. Our team will guide you to the right treatment for your skin and goals.